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Van Robichaux
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Renee Robichaux
Attorney At Law

New Study Links Isotretinoin (Accutane) Use to Ulcerative Colitis and Inflammatory Bowel Disease


An article entitled "Isotretinoin Use and the Risk of Inflammatory Bowel Disease: A Case - Control Study" recently published in The American Journal of Gastroenterology concludes that Ulcerative Colitis (UC) and Inflammatory Bowel Disease (IBD) are associated with previous isotretinoin (Accutane, Amnesteem, Sotret, Claravis) exposure.

Free Accutane Case EvaluationIsotretinoin (Accutane, Amnesteem, Sotret, Claravis) is a vitamin A derivative that was approved by the FDA for the treatment of severe acne in 1982. After several reports of patients developing IBD after treatment with isotretinoin were published, IBD was subsequently listed in the package insert for Accutane as an adverse gastrointestinal effect. However, this is the first published study to conclusively associate isotretinoin use to the risk of developing IBD and UC.

In this case-control study, performed using a large insurance claims database including more than 8,000 cases of IBD, it was found that previous isotretinoin exposure was strongly associated with an increased risk of UC. Higher doses of isotretinoin, dose escalation, and longer duration of therapy were all associated with the highest risk of UC. Compared with non-users, the risk of UC was highest in those exposed to isotretinoin for more than 2 months. Thus, the risk of IBD was higher for those taking larger doses of Isotretinoin and those taking isotretinoin for longer periods of time.

The article concludes that UC is strongly associated with previous isotretinoin exposure. The study finds that clinicians prescribing isotretinoin as well as prospective patients should be aware of this possible association.

 

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General Information
First Name
Last Name
City
Zip Code
State
Country
Primary Phone
Alternate Phone
E-Mail Address
Accutane Use
Date you last used Accutane:
Medications Used
Accutane
Generic Accutane : Amnesteem, Claravis, and/or Sotret.
Diagnosis
Inflammatory Bowel Disease
Ulcerative Colitis
Crohn's Disease
Other (Please Explain)
Approximately what year was the diagnosis by a medical professional?
Please describe the nature and extent of your injuries resulting from your use of Accutane:
Questions / Comments
 
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Please be advised we do not and cannot represent you until we have had an opportunity to evaluate your potential claim. Until such time as we have a signed contract of representation from you, we do not represent you in any claim Be advised that the statute of limitations on your claim may have already expired and, if it has not, each day that passes brings you closer to the expiration of the statute of limitations. Thus, you need to act immediately in filling out the above questionnaire. We do not represent you until we have received a fully executed fee agreement.

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